Some Items of Interest to Process R&D Chemists and Engineers
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ADVERTISEMENT RETURN TO ISSUEHighlights from the ...Highlights LiteratureNEXTSome Items of Interest to Process R&D Chemists and EngineersAlan StevenAlan StevenCatSci Ltd, CBTC2, Capital Business Park, Wentloog, Cardiff CF3 2PX, U.K.More by Alan Stevenhttps://orcid.org/0000-0002-0134-0918, Carlos MateosCarlos MateosDiscovery Chemistry Research Technologies, Eli Lilly Co., Avenida de la Industria 30, 28108 Alcobendas, SpainMore Mateoshttps://orcid.org/0000-0002-0189-4136, Andrei A. ZlotaAndrei ZlotaThe Zlota Company, LLC, 97 Brooksmont Drive, Holliston, Massachusetts 01746-1770, United StatesMore Zlotahttps://orcid.org/0000-0002-2048-9187, Christopher C. NawratChristopher NawratMerck & Co. Inc., Rahway, New Jersey 07065, Nawrathttps://orcid.org/0000-0003-4550-9954, Alexandre BarthelmeAlexandre BarthelmeCenter Expertise Drug Substance, UCB Pharma, Chemin du Foriest 1, 1420 Braine-l’Alleud, BelgiumMore Barthelme, Sylvain GuizzettiSylvain GuizzettiNovAlix, Building A: Chemistry, Bioparc, Bld. Sébastien Brant, BP 30170, F-67405 Illkirch Cedex, FranceMore Guizzettihttps://orcid.org/0000-0003-4656-2431, Rik OostRik OostAPI Small Molecule R&D, Janssen Pharmaceutical Companies Johnson Johnson, Turnhoutseweg 2340 Beerse, Oost, Paul F. RichardsonPaul RichardsonPfizer, 10578 Science Center San Diego, California 09121, Richardsonhttps://orcid.org/0000-0002-3700-8749, Robert B. KargboRobert KargboUsona Institute, 277 Granada Luis Obispo, 93401, Kargbohttps://orcid.org/0000-0002-5539-6343, John Knight*John KnightJKonsult Meadow View, Cross Keys, Hereford HR1 3NT, U.K.*Email: [email protected]More KnightCite this: Org. Res. Dev. 2023, 27, 3, 383–393Publication Date (Web):March 7, 2023Publication History Received23 February 2023Published online7 March inissue 17 2023https://doi.org/10.1021/acs.oprd.3c00060Copyright © Published 2023 American Chemical SocietyRIGHTS PERMISSIONSArticle Views4079Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are COUNTER-compliant sum full text article downloads since November 2008 (both PDF HTML) across all institutions individuals. These metrics regularly updated reflect usage leading up last few days.Citations number other articles citing this article, calculated Crossref daily. Find more information about citation counts.The Altmetric Attention Score is a quantitative measure attention that research has received online. Clicking on donut icon will load page at altmetric.com with additional details score social media presence for given article. how calculated. Share Add toView InAdd Full Text ReferenceAdd Description ExportRISCitationCitation abstractCitation referencesMore Options onFacebookTwitterWechatLinked InReddit (4 MB) Get e-Alertsclose e-Alerts
منابع مشابه
Highlights from the Literature Some Items of Interest to Process R&D Chemists and Engineers
Chung and co-workers at Merck report on an efficient five-step synthesis of a challenging 1,6-naphthyridone 5 (J. Org. Chem. 2005, 70, 10342-10347). Compound 5 is an intermediate in a synthesis of a p38 mitogen-activated protein (MAP) kinase inhibitor. The synthesis begins with a selective monoamidation of acetonedicarboxylate (ADC) dimethyl ester 1. The in situ formation of the enolate of 1 se...
متن کاملSome Items of Interest to Process R&D Chemists and Engineers ■ COPPER-CATALYZED TRIFLUOROMETHYLATION OF BORONIC ACIDS WITH TRIFLUOROMETHYL IODIDE A mild method for the cross-coupling of arylboronic acids with CF3I via the merger of photoredox
A mild method for the cross-coupling of arylboronic acids with CF3I via the merger of photoredox (to generate CF3 radical) and Cu catalysis (to generate reactive Cu−aryl species) was developed by Professor Sanford and her co-worker of University of Michigan (J. Am. Chem. Soc. 2012, 134, 9034− 9037). Potassium carbonate was found a base of choice for the promotion of transmetalation in DMF solve...
متن کاملDoctor Roderigo Lopes. Some items of medico-historical interest.
have been the result of tophi-large deposits of chalky concretions composed of needle-shaped crystals of monosodium urate. Unfortunately, if any tophi survived after two millennia in the soil, they were not recognized at the excavation and subsequent cleaning of the skeleton. It will be noted from the above description and from the plates that many of the lesions are not strictly para-articular...
متن کاملextensions of some polynomial inequalities to the polar derivative
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15 صفحه اولsome properties of fuzzy hilbert spaces and norm of operators
in this thesis, at first we investigate the bounded inverse theorem on fuzzy normed linear spaces and study the set of all compact operators on these spaces. then we introduce the notions of fuzzy boundedness and investigate a new norm operators and the relationship between continuity and boundedness. and, we show that the space of all fuzzy bounded operators is complete. finally, we define...
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ژورنال
عنوان ژورنال: Organic Process Research & Development
سال: 2023
ISSN: ['1083-6160', '1520-586X']
DOI: https://doi.org/10.1021/acs.oprd.3c00060